Laboratory testing showed elevations in serum direct and total bilirubin and a cholestatic pattern of enzyme elevations. Management of Graves Thyroidal and Extrathyroidal Disease: An Update. Withdrawal from depressants may also bring about mental health symptoms such as anxiety, perceptual disturbances, hallucinations, and other perceptual disturbances, or delirium. Recovery is usually rapid once methimazole is stopped, and the first priority should be immediate discontinuation of antithyroid therapy at the first sign of clinically apparent liver disease. Chalana H, Kundal T, Gupta V, Malhari AS. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Withdrawal symptoms of suddenly stopping certain antidepressants include anxiety, chills, difficulty sleeping, dizziness, headaches, increased depression symptoms, irritability, muscle aches, nausea, sensations of electric shock, sleepiness, and vivid dreams. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Heidari R, Niknahad H, Jamshidzadeh A, Abdoli N. Factors affecting drug-induced liver injury: antithyroid drugs as instances. Propranolol therapy was restarted but methimazole was held. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Keep this medication in the container it came in, tightly closed, and out of reach of children. Pregnancy affects the way your body metabolizes methadone, so your dose may need adjusting as your pregnancy advances. Prognostic value of thyrotropin receptor antibodies (TRAb) in Graves' disease: a 120 months prospective study. doi: 10.1046/j.1365-2265.1996.d01-1563.x. Gallelli L, Staltari O, Palleria C, De Sarro G, Ferraro M. Hepatotoxicity induced by methimazole in a previously healthy patient. All rights reserved. What should I know about storage and disposal of this medication? Methadone maintenance treatment. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Common Methimazole side effects: Drug ineffective: 348 reports Hyperthyroidism (over activity of the thyroid gland): 336 reports Fatigue (feeling of tiredness): 320 reports Weakness: 271 reports Agranulocytosis (a deficiency of granulocytes in the blood, causing increased vulnerability to infection): 262 reports Headache (pain in head): 252 reports
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